Antimicrobial resistance (AMR)

Health Management Glossary

Public Health and Policy

Definition. Antimicrobial resistance is the ability of bacteria, viruses, fungi and parasites to survive medicines that were previously effective against them.

Explanation

Resistance arises through natural selection and spreads faster when antimicrobials are overused or misused in human medicine, agriculture and animal health. The World Health Organization treats it as a One Health problem that requires action across sectors.

The Global Research on Antimicrobial Resistance collaborators estimated that bacterial AMR was directly responsible for about 1.27 million deaths in 2019 (Antimicrobial Resistance Collaborators, 2022). In hospitals, responses combine infection prevention, surveillance and antimicrobial stewardship.

Related concepts

Global health

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References

Antimicrobial Resistance Collaborators. (2022). Global burden of bacterial antimicrobial resistance in 2019: A systematic analysis. The Lancet, 399(10325), 629–655.

O’Neill, J. (2016). Tackling drug-resistant infections globally: Final report and recommendations. Review on Antimicrobial Resistance.

World Health Organization. (2015). Global action plan on antimicrobial resistance. WHO.

Cite this entry: Kurutkan, M. N. (2026). Antimicrobial resistance. In The Health Topics glossary. https://healthtopic.org/glossary/antimicrobial-resistance/

Articles that discuss this concept

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