Moderation analysis

Health Management Glossary

Research Methods

Definition. Moderation analysis tests whether the strength or direction of a relationship between two variables depends on a third variable, the moderator.

Explanation

Moderation is modelled with interaction terms and probed with simple slopes or conditional effects (Hayes, 2018). In safety research, abusive supervision and safety consciousness have been tested as moderators of leadership effects on safety behaviour (Zheng et al., 2022), and cognitive function moderates the link between digital inclusion and depression risk in older adults (Xiao & Nie, 2025).

Related concepts

Mediation analysis Structural equation modeling (SEM) PLS-SEM Effect size

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References

Hayes, A. F. (2018). Introduction to mediation, moderation, and conditional process analysis: A regression-based approach (2nd ed.). Guilford Press.

Xiao, G., & Nie, T. (2025). The critical moderating role of cognitive function in digital inclusion: Data analysis study on depression risk among older adults. JMIR Aging, 8, Article e80700. https://doi.org/10.2196/80700

Zheng, J., Gou, X., Griffin, M. A., Goh, Y. M., & Xia, N. (2022). Temporal leadership, attentiveness, and safety behaviors: the moderating roles of abusive supervision and safety consciousness. Safety Science, 147, 105633.

Cite this entry: Kurutkan, M. N. (2026). Moderation analysis. In The Health Topics glossary. https://healthtopic.org/glossary/moderation-analysis/

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